-Saint Anthony Hospital was started by the Sisters of the Third Order of Saint Francis at the request of Rockford community leaders
-Saint Anthony Hospital was originally located at East State and Summit Streets in Rockford and was later relocated to the current site of OSF Saint Anthony Medical Center
-Innovative firsts for the Rockford area performed by the physicians affiliated with OSF Saint Anthony Medical Center include open-heart and beating heart bypass surgeries; innovative valve-replacement cardiac surgery; implantable cardiac defibrillators; total hip replacement surgeries; brachytherapy radiation therapy for prostate and lung cancer; implantable pain-relief devices and the use of artificial skin for burn patients
-Other medical firsts at OSF Saint Anthony include artificial spine disc replacement; MicroMaze cardiac surgery; transmyocardial laser revascularization (TMR); intraoperative cerebral angiograms; MammoSite breast cancer treatment; balloon kyphoplasty to treat spinal fractures; 3-dimensional CT scans that provide fast diagnosis of cardiovascular and neurological diseases; and new technology that improves total knee replacement surgery
-OSF Saint Anthony Medical Center is a member of OSF HealthCare, an affiliate corporation of The Sisters of the Third Order of St. Francis.